LAG3 Protein, Mouse, Recombinant (His Tag)

1/1
Price:
Size:
Number:

LAG3 Protein, Mouse, Recombinant (His Tag): 製品情報

純度
> 90 % as determined by SDS-PAGE.
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
活性
Testing in progress
タンパク質の構築
A DNA sequence encoding the mouse LAG3 (NP_032505.1) (Met1-Arg432) was expressed with a polyhistidine tag at the C-terminus.
NP No.
発現ホスト
HEK293 Cells
Mouse
予測N末端
Gly 24
分子量
The recombinant mouse LAG3 consists of 420 amino acids and predicts a molecular mass of 45.7 kDa.
バッファー
Lyophilized from sterile PBS, pH 7.4.
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
配送
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
安定性 & 保存条件
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
再構成
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

LAG3 Protein, Mouse, Recombinant (His Tag): 画像

LAG3 Protein, Mouse, Recombinant (His Tag): 別名

CD223 Protein, Mouse; LAG-3 Protein, Mouse; Ly66 Protein, Mouse

LAG3 背景情報

LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo.
完全な名称
lymphocyte-activation gene 3
参考文献
  • Sigrid Hannier. et al., 1998, The Journal of Immunology. 161(8): 4058-65.
  • Triebel F. et al., 1990, J Exp Med. 171 (5): 1393-405.
  • Baixeras E. et al., 1992, J Exp Med. 176 (2): 327-37.
  • Huard B. et al., 1997, Proc Natl Acad Sci. 94 (11): 5744-9.
  • Kisielow M. et al., 2005, Eur J Immunol. 35 (7): 2081-8.
カートに追加しました カートに追加しませんでした カートを更新しています。少々お待ちください