Human Leukocyte Differentiation Antigen workshop Ⅳ / HLDA4

The Human Leukocyte Differentiation Antigen workshop Ⅳ (HLDA4), held in Vienna, Austria, in 1989. HLDA4 greement was reached on 35 new CD clusters and subclusters. In addition, seven previously established clusters were redefined.The following list should provide the reader with an up-to-date list of the new CD designationst and some basic information concerning the molecules defined by these antibodies. Detailed reports will be published separately as will a new database/evaluation program.

New CD antigens list of HLDA4

New CD Alias Function
CD46 MCP, TLX Inhibitory complement activation
CD47 IAP, MER6 Cell adhesion and signal transduction
CD48 Blast-1, BCM1 Cell adhesion and T-cell costimulation
CDw49b
CDw49d
CDw49f
CDw50
CD51 Vitronectin receptor, ITGAV, MSK8 Adhesion and signal transduction
CDw52
CD53 Tetraspanin-25, MOX44 Signal transduction. Cell adhesion, activation, and migration
CD54 ICAM-1 Cell adhesion, lymphocyte activation, and migration
CD55 DAF Regulates complement activation. Signal transduction
CD56 NCAM1 Homophilic and heterophilic adhesion
CD57 B3GAT1, GLCATP, GLCUATP, HNK1, LEU7, NK-1, NK1 Adhesion molecule.
CD58 LFA-3 APC-T-cell adhesion. Killer target cell interaction.
CD59 Protectin, MAC- inhibitor Prevents complement polymerization. Protects cells from complement mediated lysis
CDw60
CD61 GPIIIa, ITGB3, GP3A Cell adhesion
CD62
CD63 LIMP, LAMP-3, MLA1 Cell growth and motility regulation; complexes with integrins
CD64 FcγRI, FCGR1, FCGR1A Innate and adaptive immune responses
CDw65
CD66
CD67
CD68 Macrosialin, gp110, KP1 Macrophage homing
CD69 AIM, CLEC2C, EA1 Signal transmission in NK cells and platelets
CDw70
CD71 T9, TFRC Controls iron uptake during cell proliferation
CD72 Lyb-2, Ly-19, Ly-32 B-cell activation and proliferation
CD73 5'-nucleotidase, NT5E Nucleotidase
CD74 LN2, Ii, DHLAG MHC class II antigen processing
CDw75
CD76
CD77 Gb3, Pk blood group, BLA,A4GALT Induces apoptosis
CDw78

Other Human Leukocyte Differentiation Antigen workshops

CD antigens / Cluster of differentiation
CD antigens
CD antigens reagent products
Non-CD cellular antigens
Clusters of differentiation
human Leukocyte Differentiation Antigen workshop
human Leukocyte Differentiation Antigen workshop I
human Leukocyte Differentiation Antigen workshop II
human Leukocyte Differentiation Antigen workshop III
human Leukocyte Differentiation Antigen workshop IV
human Leukocyte Differentiation Antigen workshop V
human Leukocyte Differentiation Antigen workshop VI
human Leukocyte Differentiation Antigen workshop Ⅶ
human Leukocyte Differentiation Antigen workshop Ⅷ
human Leukocyte Differentiation Antigen workshop IX
human Leukocyte Differentiation Antigen workshop Ⅹ