Fetuin B Protein, Mouse, Recombinant (His Tag)

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Fetuin B Protein, Mouse, Recombinant (His Tag): 製品情報

純度
> 97 % as determined by SDS-PAGE
内毒素
< 1.0 EU per μg of the protein as determined by the LAL method
活性
Testing in progress
タンパク質の構築
A DNA sequence encoding the extracellular domain of mouse FETUB (Q9QXC1-1) (Met 1-Pro 388) was expressed, with a polyhistidine tag at the C-terminus.
NCBI Reference No.
発現ホスト
HEK293 Cells
Mouse
予測N末端
Arg 19
分子量
The recombinant mouse FETUB consists of 381 amino acids and has a predicted molecular mass of 42.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmFETUB is approximately 55-60 kDa due to high glycosylation.
バッファー
Lyophilized from sterile 20mM Tris, 150mM NaCl, pH 7.5
Please contact us for any concerns or special requirements.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
配送
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
安定性 & 保存条件
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
再構成
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Fetuin B Protein, Mouse, Recombinant (His Tag): 画像

Fetuin B Protein, Mouse, Recombinant (His Tag): 別名

2310011O17Rik Protein, Mouse; AI255764 Protein, Mouse; D17980 Protein, Mouse; Gugu Protein, Mouse

Fetuin B 背景情報

Fetuin-B, also known as Fetuin-like protein IRL685 and FETUB, is a secreted protein which belongs to thefetuin family. Fetuin-B / FETUB contains twocystatin domains. Fetuin-B is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption. Fetuin-A has been identified as a major protein during fetal life and is also involved in important functions such as protease inhibitory activities and development-associated regulation of calcium metabolism and osteogenesis. Fetuin-A is a key partner in the recovery phase of an acute inflammatory response. Fetuin-B / FETUB is found at least in human and rodents. It is unambiguously a paralogue of Fetuin-A. Fetuin-A and Fetuin-B exhibit significant differences at the amino acid sequence level, notably including variations with respect to the archetypal fetuin-specific signature.
完全な名称
fetuin B
参考文献
  • Olivier E., et al., 2000, Biochem. J. 350:589-97
  • Liu T., et al., 2005, J. Proteome Res. 4:2070-80.
  • Hsu SJ, et al., 2005, Genome. 47 (5): 931-46.
  • Liu T, et al., 2006, J. Proteome Res.4 (6): 2070-80.
  • Maternal malnourishment induced upregulation of fetuin-B blunts nephrogenesis in the low birth weight neonate
    Author
    Rabadi, MM;Abdulmahdi, W;Nesi, L;Jules, E;Marghani, Y;Sheinin, E;Tilzer, J;Gupta, S;Chen, S;Cassimatis, ND;Lipphardt, M;Kozlowski, PB;Ratliff, BB;
    Year
    2018
    Journal
    Dev. Biol.
    Application
    animal-based
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