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PAX8 抗体, ウサギポリクローナル抗体

発現宿主: E. coli  
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100 µg 
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PAX8 antibody 背景

PAX8 gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. PAX8 is involved in thyroid follicular cell development and expression of thyroid-specific genes. Also functions in very early stages of kidney organogenesis. Mutations in PAX8 gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

人々 PAX8 antibody 参考文献
  • Poleev A. et al., 1995, Eur J Biochem. 228 (3): 899-911
  • Poleev A. et al., 1993, Development. 116 (3): 611-23.
  • Di Palma. et al., 2003, J Biol Chem. 278 (5): 3395-402.
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