Cluster of differentiation in platelet

Platelets are anucleate blood cells that play a crucial role in the maintenance of hemostasis. While platelet activation and elevated platelet counts are associated with increased risk of thrombotic complications, low platelet counts and several platelet function disorders increase the risk of bleeding. Platelets and their activation state can also modulate innate and adaptive immune responses and low platelet counts have been identified as a surrogate marker for poor prognosis in septic patients.

Platelet surface markers: appear on the platelet surface before activation. Some useful are CD41, CD42a , CD42b, and CD61. Platelet activation markers: appear on the platelet surface during activation. Some useful are CD62P, CD31 and CD63. Some assays of platelet function are best achieved with flow cytometry. Platelet can be further accelerated by CD40 ligand (CD154) binding to CD40. Platelets express and secrete CD154, thereby triggering host responses and boosting inflammation.

CD antigens / Cluster of differentiation
CD antigens
CD antigens reagent products
Non-CD cellular antigens
Clusters of differentiation
what is cluster of differentiation
cluster of differentiation nomenclature
cluster of differentiation as markers
cluster of differentiation function
cluster of differentiation classification by Immunophenotyping+
- cluster of differentiation in stem cells
- cluster of differentiation in granulocyte
- cluster of differentiation in monocyte
- cluster of differentiation in T lymphocyte
- cluster of differentiation in helper T cell
- cluster of differentiation in regulatory T cell
- cluster of differentiation in cytotoxic T cell
- cluster of differentiation in B lymphocyte
- cluster of differentiation in platelet
- cluster of differentiation in NK cell
cluster of differentiation 4 / CD4
cluster of differentiation 8 / CD8
cluster of differentiation 3 / CD3
clusters of differentiation of the B7 family
clusters of differentiation of FC receptor
human Leukocyte Differentiation Antigen workshop