Cluster of differentiation 3δ/ CD3δ

CD3 proteins may have redundant as well as specific contributions to the intracellular propagation and final effector responses of TCR-mediated signals at different checkpoints during T cell differentiation. However, to date, the relative role that each CD3 chain plays in signaling is controversial. The patients with CD3γ deficiency can present with different clinical findings despite having the same homozygous mutation. In order to examine the roles of CD3γ chain in TCR signaling, CD3γ can propagate a number of signals through the remaining invariant chains, likely the homologous CD3δ chain, which replaces it at the mutant TCR.

CD3γ / CD3g / CD3 gamma Antibody, Rabbit PAb, Antigen Affinity Purified by WB Application

Caption: Immunochemical staining of human CD3D in human spleen with mouse Mab (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of T cells.

CD antigens / Cluster of differentiation
CD antigens
CD antigens reagent products
Non-CD cellular antigens
Clusters of differentiation
what is cluster of differentiation
cluster of differentiation nomenclature
cluster of differentiation as markers
cluster of differentiation function
cluster of differentiation classification by Immunophenotyping
cluster of differentiation 4 / CD4
cluster of differentiation 8 / CD8
cluster of differentiation 3 / CD3+
- cluster of differentiation 3γ
- cluster of differentiation 3δ
- cluster of differentiation 3ε
clusters of differentiation of the B7 family
clusters of differentiation of FC receptor
human Leukocyte Differentiation Antigen workshop