UBXN4 cDNA ORF Clone, Mouse, N-DYKDDDDK (Flag®) tag

UBXN4 cDNA ORF Clone, Mouse, N-DYKDDDDK (Flag®) tag: 製品情報

遺伝子
Mouse
NCBI 参考シーケンス番号
遺伝子の長さ
1521 bp
製品の特徴
Full length Clone DNA of Mouse UBX domain protein 4 with N terminal Flag tag.
プラスミド
プロモーター
Enhanced CMV promoter
ベクター
タグシーケンス
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
シークエンシングプライマー
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Kanamycin
細胞スクリーニング抵抗力
Hygromycin
アプリケーション
Stable or Transient mammalian expression
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.
Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.

UBXN4 cDNA ORF Clone, Mouse, N-DYKDDDDK (Flag®) tag: 別名

1300013G12Rik cDNA ORF Clone, Mouse; mKIAA0242 cDNA ORF Clone, Mouse; Ubxd2 cDNA ORF Clone, Mouse

UBXN4 背景情報

UBXN4 (UBX Domain Protein 4) is a Protein Coding gene. The UBXN4 gene, located on 2q21.3, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, and frog. UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP) and promotes ER-associated protein degradation (ERAD). UBXD2 acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD. UBXN4 is widely expressed in the thyroid, gall bladder, and other tissues. Diseases associated with UBXN4 include Martsolf Syndrome. An important paralog of this gene is TNRC6A. 238 organisms have orthologs with the human gene UBXN4.
完全な名称
UBX domain protein 4
参考文献
  • Mueller B, et al. (2008) Sel1l nucleates a protein complex required for dislocation of misfolded glycoproteins. Proc Natl Acad Sci U S A 105 (34): 12325-12330.
  • Madsen L, et al. (2014) Human aspl/tug interacts with p97 and complements the proteasome mislocalization of a yeast ubx4 mutant, but not the er-associated degradation defect. BMC Cell Biol 15 31.
  • Li X, et al. (2012) A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries. Hum Mol Genet 21 (2): 421-429.

UBXN4 cDNA ORFクローン, Rat, 関連製品

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