SLC38A1 cDNA ORF Clone in Cloning Vector, Mouse

SLC38A1 cDNA ORF Clone in Cloning Vector, Mouse: 製品情報

遺伝子
Mouse
NCBI 参考シーケンス番号
遺伝子の長さ
1458 bp
シーケンスの特徴
Identical with the Gene Bank Ref. ID sequence.
製品の特徴
Full length Clone DNA of Mouse solute carrier family 38, member 1.
プラスミド
ベクター
シークエンシングプライマー
SP6 and T7 or M13-47 and RV-M
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Ampicillin
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

SLC38A1 cDNA ORF ヌクレオチド配列およびアミノ酸配列に関する情報

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

SLC38A1 cDNA ORF Clone in Cloning Vector, Mouse: 別名

AA408026 cDNA ORF Clone, Mouse; AA409865 cDNA ORF Clone, Mouse; AL022800 cDNA ORF Clone, Mouse; AU015942 cDNA ORF Clone, Mouse; NAT2 cDNA ORF Clone, Mouse

SLC38A1 背景情報

SLC38A1 (Solute Carrier Family 38 Member 1) is a Protein Coding gene. The SLC38A1 gene, located on 12q13.11, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate. SLC38A1 is widely expressed in the lymph node, thyroid, and other tissues. Diseases associated with SLC38A1 include Klatskin's Tumor. SLC38A1 is associated with the occurrence and progression of solid tumors. Further, glutamine transporter SLC38A1 might serve as a potential target for the development of novel therapeutic drugs in the treatment of acute myeloid leukemia (AML).
完全な名称
solute carrier family 38, member 1
参考文献
  • Qureshi T, et al. (2020) Slc38a1 conveys astroglia-derived glutamine into gabaergic interneurons for neurotransmitter gaba synthesis. Cells 9 (7): 1686.
  • Qureshi T, et al. (2019) The glutamine transporter slc38a1 regulates gabaergic neurotransmission and synaptic plasticity. Cereb Cortex 29 (12): 5166-5179.
  • Li Y, et al. (2019) High expression of slc38a1 predicts poor prognosis in patients with de novo acute myeloid leukemia. J Cell Physiol 234 (11): 20322-20328.
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