HDAC1 cDNA ORF Clone, Mouse, C-DYKDDDDK (Flag®) tag

HDAC1 cDNA ORF Clone, Mouse, C-DYKDDDDK (Flag®) tag: 製品情報

遺伝子
Mouse
NCBI 参考シーケンス番号
遺伝子の長さ
1488 bp
シーケンスの特徴
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 588G/A not causing the amino acid variation.
製品の特徴
Full length Clone DNA of Mouse histone deacetylase 1 with C terminal Flag tag.
プラスミド
プロモーター
Enhanced CMV promoter
ベクター
制限部位
KpnI + XbaI(6kb+1.49kb)
タグシーケンス
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
シークエンシングプライマー
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Kanamycin
細胞スクリーニング抵抗力
Hygromycin
アプリケーション
Stable or Transient mammalian expression
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.
Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.

HDAC1 cDNA ORF ヌクレオチド配列およびアミノ酸配列に関する情報

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

HDAC1 cDNA ORF Clone, Mouse, C-DYKDDDDK (Flag®) tag: 検証済の画像

HDAC1 cDNA ORF Clone, Mouse, C-DYKDDDDK (Flag®) tag: 別名

HD1 cDNA ORF Clone, Mouse; Hdac1-ps cDNA ORF Clone, Mouse; MommeD5 cDNA ORF Clone, Mouse; RPD3 cDNA ORF Clone, Mouse

HDAC1 背景情報

HDAC1 (Histone Deacetylase 1) is a Protein Coding gene. Histone Deacetylase 1 protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. HDAC1 is a ubiquitous deacetylase enzyme responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4). Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. HDAC1 is widely expressed in the lymph node, colon, and other tissues. Diseases associated with HDAC1 include Atrichia With Papular Lesions and Retinoblastoma.
完全な名称
histone deacetylase 1
研究分野
Related Pathways
  • Notch Signaling
    Notch Signaling
  • p53 Pathway
    p53 Pathway
参考文献
  • Beharry AW, Sandesara PB, Roberts BM, Ferreira LF, Senf SM, Judge AR. HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy. Journal of Cell Science. 2014;127(7):1441-1453.
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