Galectin 3/LGALS3 cDNA ORF Clone in Cloning Vector, Mouse

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Galectin 3/LGALS3 cDNA ORF Clone in Cloning Vector, Mouse: 製品情報

遺伝子
Mouse
NCBI 参考シーケンス番号
遺伝子の長さ
795 bp
シーケンスの特徴
Identical with the Gene Bank Ref. ID sequence except for six point mutations: 117 T/C, 132 C/T, 141 A/G, 186C/T, 546 G/A and 627 C/A not causing the amino acid variation.
製品の特徴
Full length Clone DNA of Mouse lectin, galactose binding, soluble 3.
プラスミド
ベクター
シークエンシングプライマー
M13-47 and RV-M
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Ampicillin
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

Galectin 3/LGALS3 cDNA ORF ヌクレオチド配列およびアミノ酸配列に関する情報

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Galectin 3/LGALS3 cDNA ORF Clone in Cloning Vector, Mouse: 別名

gal3 cDNA ORF Clone, Mouse; GBP cDNA ORF Clone, Mouse; L-34 cDNA ORF Clone, Mouse; Mac-2 cDNA ORF Clone, Mouse

Galectin 3/LGALS3 背景情報

LGALS3, a member of the lectin family, has an important role in tumor progression through inhibition of apoptosis.The galectin-3 gene (LGALS3) encodes a beta-galactose binding lectin. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Galectin-3 is a beta-galactoside-binding lectin which is involved in modulating inflammation and apoptosis. Elevated expression of galectin-3 has been demonstrated in synovium of rheumatoid arthritis (RA).
完全な名称
lectin, galactoside-binding, soluble, 3
参考文献
  • Dumic J, et al. (2006) Galectin-3: an open-ended story. Biochim Biophys Acta. 1760(4): 616-35.
  • Sharma UC, et al. (2004) Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation. 110(19): 3121-8.
  • Yan YP, et al. (2009) Galectin-3 mediates post-ischemic tissue remodeling. Brain Res. 1288: 116-24.
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