CD3G cDNA ORF Clone in Cloning Vector, Mouse

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CD3G cDNA ORF Clone in Cloning Vector, Mouse: 製品情報

遺伝子
Mouse
NCBI 参考シーケンス番号
遺伝子の長さ
549 bp
シーケンスの特徴
Identical with the Gene Bank Ref. ID sequence except for two point mutations: 543 G/T(K181N), 279 A/G causing the amino acid variation.
製品の特徴
Full length Clone DNA of Mouse CD3 antigen, gamma polypeptide.
プラスミド
ベクター
シークエンシングプライマー
M13-47 and RV-M
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Ampicillin
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

CD3G cDNA ORF ヌクレオチド配列およびアミノ酸配列に関する情報

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

CD3G cDNA ORF Clone in Cloning Vector, Mouse: 別名

Ctg-3 cDNA ORF Clone, Mouse; Ctg3 cDNA ORF Clone, Mouse; T3g cDNA ORF Clone, Mouse

CD3G 背景情報

CD3G gene encodes CD3-gamma polypeptide, which together with CD3-epsilon, -delta, and -zeta, and the TCR alpha/beta and gamma/delta heterodimers, forms the TCR-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The CD3 gamma chain has long been considered to mediate targeting to lysosomes for degradation. Defects in this gene are associated with T cell immunodeficiency. Further, it has been proposed as one of the important candidate genes for cancer development due to its pivotal roles in TCR signaling pathway.
完全な名称
CD3g molecule, gamma (CD3-TCR complex)
Related Pathways
  • T Cell Receptor Signaling Pathway
    T Cell Receptor Signaling Pathway
参考文献
  • Jiang L, Xu J, Ni J, et al. A Functional Insertion/Deletion Polymorphism in the Proximal Promoter of CD3G Is Associated with Susceptibility for Hepatocellular Carcinoma in Chinese Population. DNA and Cell Biology.
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