Serglycin cDNA ORF Clone, Human, C-Myc tag

Serglycin cDNA ORF Clone, Human, C-Myc tag: 製品情報

遺伝子
Human
NCBI 参考シーケンス番号
遺伝子の長さ
477 bp
製品の特徴
Full length Clone DNA of Human serglycin with C terminal Myc tag.
プラスミド
プロモーター
Enhanced CMV promoter
ベクター
タグシーケンス
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
シークエンシングプライマー
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Kanamycin
細胞スクリーニング抵抗力
Hygromycin
アプリケーション
Stable or Transient mammalian expression
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

Serglycin cDNA ORF Clone, Human, C-Myc tag: 別名

PPG cDNA ORF Clone, Human; PRG cDNA ORF Clone, Human; PRG1 cDNA ORF Clone, Human

Serglycin 背景情報

SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.
完全な名称
serglycin
参考文献
  • Hatton MN. et al., 1985, Biochem J. 230 (3): 817-20.
  • Schick BP. et al., 1995, J Cell Physiol. 165 (1): 96-106.
  • Kato S. et al., 1995, Gene. 150 (2): 243-50.
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