PIK3CA cDNA ORF Clone, Human, untagged
Cat: HG11910-UT
PIK3CA cDNA ORF Clone, Human, untagged: 製品情報
遺伝子
種
Human
NCBI 参考シーケンス番号
遺伝子の長さ
3207 bp
シーケンスの特徴
Identical with the Gene Bank Ref. ID sequence.
製品の特徴
Full length Clone DNA of Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
プラスミド
プロモーター
Enhanced CMV promoter
ベクター
制限部位
KpnI+NotI(6.1kb+3.21kb)
シークエンシングプライマー
T7( 5' TAATACGACTCACTATAGGG 3' ) BGH( 5' TAGAAGGCACAGTCGAGG 3' )
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Ampicillin
細胞スクリーニング抵抗力
Hygromycin
アプリケーション
Stable or Transient mammalian expression
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.
PIK3CA cDNA ORF ヌクレオチド配列およびアミノ酸配列に関する情報
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
PIK3CA cDNA ORF Clone, Human, untagged: 検証済の画像
PIK3CA cDNA ORF Clone, Human, untagged: 別名
CLAPO cDNA ORF Clone, Human; CLOVE cDNA ORF Clone, Human; CWS5 cDNA ORF Clone, Human; MCAP cDNA ORF Clone, Human; MCM cDNA ORF Clone, Human; MCMTC cDNA ORF Clone, Human; p110-alpha cDNA ORF Clone, Human; PI3K cDNA ORF Clone, Human; PI3K-alpha cDNA ORF Clone, Human
PIK3CA 背景情報
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 11 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.
完全な名称
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
研究分野
Related Pathways
-
Actin Dynamics Signaling Pathway -
AKT Signaling Pathway -
AMPK Signaling Pathway -
B Cell Receptor Signaling Pathway -
G Protein-coupled Receptors Signaling -
Jak-Stat Signaling Pathway -
MAPK-Erk Pathway -
T Cell Receptor Signaling Pathway -
Common G-Chain signaling pathway
参考文献
- Limaye N, Kangas J, Mendola A, et al. Somatic Activating PIK3CA Mutations Cause Venous Malformation. American Journal of Human Genetics. 2015;97(6):914-921.
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