CD48 cDNA ORF Clone, Human, N-HA tag

Price:
Size:
Number:

CD48 cDNA ORF Clone, Human, N-HA tag: 製品情報

遺伝子
Human
NCBI 参考シーケンス番号
遺伝子の長さ
732 bp
製品の特徴
Full length Clone DNA of Human CD48 molecule with N terminal HA tag.
プラスミド
プロモーター
Enhanced CMV promoter
ベクター
タグシーケンス
HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
シークエンシングプライマー
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Kanamycin
細胞スクリーニング抵抗力
Hygromycin
アプリケーション
Stable or Transient mammalian expression
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

CD48 cDNA ORF Clone, Human, N-HA tag: 別名

BCM1 cDNA ORF Clone, Human; BLAST cDNA ORF Clone, Human; Blast-1 cDNA ORF Clone, Human; BLAST1 cDNA ORF Clone, Human; hCD48 cDNA ORF Clone, Human; mCD48 cDNA ORF Clone, Human; MEM-102 cDNA ORF Clone, Human; SLAMF2 cDNA ORF Clone, Human

CD48 背景情報

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
完全な名称
CD48 molecule
研究分野
参考文献
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
カートに追加しました カートに追加しませんでした カートを更新しています。少々お待ちください U.S.A.