Recombinant Mouse CD38 protein (Catalog#50191-M08H)
Produced in rabbits immunized with purified, recombinant Mouse CD38 (rM CD38; Catalog#50191-M08H; NP_031672.2; Leu 45-Thr 304). CD38 specific IgG was purified by mouse CD38 affinity chromatography
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Please Note: Optimal concentrations/dilutions should be determined by the end user.
Anti-CD38 Antibody (Rabbit Polyclonal 抗体) の画像
Immunochemical staining of mouse CD38 in mouse kidney with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections). Positive staining was localized to endotheliocyte.
Immunochemical staining of mouse CD38 in mouse heart with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections). Positive staining was localized to endotheliocyte.
Flow cytometric analysis of CD38 expression on spleen lymphocytes. BALB/c splenocytes were stained with Mouse CD38 Affinity Purified Polyclonal Ab (50191-RP02), then a FITC-conjugated second step antibody. The histogram were derived from the gated events based on light scattering characteristics of lymphocytes.
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 32 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.