TRAF6 Antibodies, cDNA Clones Research Reagents

All TRAF6 reagents are produced in house and quality controlled, including 1 TRAF6 Antibody, 5 TRAF6 Gene, 1 TRAF6 IP Kit. All TRAF6 reagents are ready to use.

TRAF6 Antibody (1)

    TRAF6 cDNA Clone (5)

    NM_145803.2

    In expression vector

    In lentiviral vector

    NM_001303273.1

    In expression vector

    TRAF6 の背景知識

    Tumor necrosis factor receptor-associated factor 6 (TRAF6) is an essential component of the signaling complex that mediates osteoclastogenesis. As an adaptor protein of E3 ligase function, TRAF6 regulates NF-kappaB signaling via TAK1 and I-kappaB kinase (IKK) activation. TRAF6 (TNF receptor associated factor 6) plays a pivotal role in NFKB activation and macroautphagy/autophagy activation induced by TLR4 (toll like receptor 4) signaling. TRAF6 is one of the key adapter molecules in Toll-like receptor signal transduction that triggers downstream cascades involved in innate immunity.

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