Transferrin Receptor/TFRC (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All Transferrin Receptor/TFRC reagents are produced in house and quality controlled, including 27 Transferrin Receptor/TFRC Antibody, 54 Transferrin Receptor/TFRC Gene, 3 Transferrin Receptor/TFRC IP Kit, 5 Transferrin Receptor/TFRC Lysate, 6 Transferrin Receptor/TFRC Protein, 3 Transferrin Receptor/TFRC qPCR. All Transferrin Receptor/TFRC reagents are ready to use.

All Transferrin Receptor/TFRC Reagents

Transferrin Receptor/TFRC Protein (6)

    Transferrin Receptor/TFRC Antibody (27)

      Transferrin Receptor/TFRC cDNA Clone (54)

      NM_001128148.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_011638.4

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_022712.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_001257303.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      Transferrin Receptor/TFRC Lysate (5)

        Transferrin Receptor/TFRC の背景知識

        Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.

        Transferrin Receptor/TFRC の参考文献

        • Douabin-Gicquel V., et al., 2001,Hum. Genet. 109:393-401.
        • Ryschich,E. et al., 2004,Eur J Cancer. 40 (9):1418-22.
        • Tosoni D., et al., 2005, Cell 123:875-888.
        • Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.

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