TARC Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All TARC reagents are produced in house and quality controlled, including 7 TARC Antibody, 2 TARC ELISA, 39 TARC Gene, 4 TARC Lysate, 4 TARC Protein, 2 TARC qPCR. All TARC reagents are ready to use.

TARC Protein (4)

    TARC Antibody (7)

      TARC ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(2)

      TARC cDNA Clone (39)

      NM_002987.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_011332.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_001032852.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      TARC Lysate (4)

        TARC の背景知識

        Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.

        TARC の参考文献

        • Laing KJ, et al. (2004) Chemokines. Developmental and comparative immunology. 28(5): 443-60.
        • Cocchi F, et al. (1995) Identification of RANTES, MIP-1a, and MIP-1b as the major HIV-suppressive factor produced by CD8+ T cells. Science. 270 (5243): 1811-5.
        • Morita A, et al. (2002). Evaluation of human thymus and activation-regulated chemokine concentrations in blood using a new sandwich ELISA based on monoclonal antibodies. Clin Chim Acta. 322 (1-2): 67-75.

        Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.