Survivin Proteins, Antibodies, cDNA Clones Research Reagents

All Survivin reagents are produced in house and quality controlled, including 3 Survivin Antibody, 32 Survivin Gene, 1 Survivin Protein, 1 Survivin qPCR. All Survivin reagents are ready to use.

Survivin Protein (1)

    Survivin Antibody (3)

      Survivin cDNA Clone (32)


      クローニングベクター cDNA 製品

      In lentiviral vector


      クローニングベクター cDNA 製品

      In lentiviral vector


      クローニングベクター cDNA 製品

      In lentiviral vector

      Survivin qPCR Primer (1)

      Survivin の背景知識

      BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-dependently and highly expressed at mitosis. As a multitasking protein, BIRC5 has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is a component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Survivin acts as an important regulator of the localization of this complex. It may counteract a default induction of apoptosis in G2/M phase.

      Survivin の参考文献

      • Altieri DC. 1994, J Biol Chem. 269 (5): 3139-42.
      • Bouchard BA. et al., 2002, Thromb Haemost. 86 (4): 1133-5.
      • Yao XQ. et al., 2004, World J Gastroenterol. 10 (9): 1262-7.

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