SERPINB10 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All SERPINB10 reagents are produced in house and quality controlled, including 2 SERPINB10 Antibody, 16 SERPINB10 Gene, 1 SERPINB10 Lysate, 1 SERPINB10 Protein, 1 SERPINB10 qPCR. All SERPINB10 reagents are ready to use.

SERPINB10 Protein (1)

    SERPINB10 Antibody (2)

      SERPINB10 cDNA Clone (16)

      NM_005024.1

      In expression vector

      NM_198028.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      SERPINB10 qPCR Primer (1)

      SERPINB10 Lysate (1)

        SERPINB10 の背景知識

        Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases (serine protease inhibitors). Over 1 serpins have been identified.
        Mouse SerpinB1, also known as Peptidase inhibitor 1, PI-1, Bomapin and SERPINB1, is a nucleus and cytoplasm protein which belongs to theserpin family and Ov-serpin subfamily. SerpinB1 is expressed specifically in the bone marrow. SerpinB1 is a protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. SerpinB1 is a redox-sensitive nuclear serpin that augments proliferation or apoptosis of leukaemia cells, depending on growth factors availability. SerpinB1 may regulate protease activities in the cytoplasm and in the nucleus.

        SERPINB10 の参考文献

        • Riewald M. et al., 1995, J. Biol. Chem. 270: 26754-7.
        • Forsyth, S. et al., 2003, Genomics 81: 336-45. 
        • Horvath, AJ. et al., 2004, J. Mol. Evol. 59: 488-97.
        • Steenbakkers PJ. et al., 2008, Mycol. Res. 112 (Pt 8): 999-1006.
        • Przygodzka, P. et al., 2010, BMC Cell Biol. 11: 30. 

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