Profilin 4 Proteins, cDNA Clones Research Reagents

PFN4 (Profilin Family Member 4) is a protein coding gene located on human chromosome 2p23.3. The human PFN4 gene encodes a 14319 Da protein containing 129 amino acids. The PFN4 protein is restrictedly expressed toward testis. Among its related pathways are Association Between Physico-Chemical Features and Toxicity Associated Pathways and Ras signaling pathway. PFN4 is related to actin binding and lipid binding.

Profilin 4 Protein (1)

    Profilin 4 cDNA Clone (15)


    クローニングベクター cDNA 製品

    In lentiviral vector

    Profilin 4 qPCR Primer (1)

    Profilin 4 の背景知識

    PFN4, also known as profilin 4, is a member of the profilin family. Profilin can be detected in all eukaryotic organisms. It plays an important role in the spatially and temporally controlled growth of actin microfilaments. Profilin is one of the most abundant actin monomer binders, but proteins such as CAP and (in mammals) thymosin β4 have some functional overlaps with profilin. In contrast, ADF/cofilin has some properties that antagonize profilin action. PFN4 also functions in the dynamic turnover and restructuring of the actin cytoskeleton.

    Profilin 4 の参考文献

    • Di Nardo A. et al., 2000, J Cell Sci. 113 (21): 3795-803.
    • Witke W. et al., 1998, EMBO J. 17 (4): 967-76.
    • Carlsson L. et al., 1977, J Mol Biol. 115 (3): 465-83.

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