PECR Antibodies, cDNA Clones Research Reagents

PECR (Peroxisomal Trans-2-Enoyl-CoA Reductase, also known as TERP; DCRRP; PVIARL; HPDHASE; SDR29C1; HSA250303), located on 2q35, is a Protein Coding gene. The gene produces a 32544 Da protein composed of 303 amino acids. This protein is involved in the pathway of fatty acid biosynthesis, which is part of Lipid metabolism, it has no 2,4-dienoyl-CoA reductase activity. The guinea pig, mouse, and human proteins share 71 to 75% amino acid identity. Diseases such as Ehlers-Danlos Syndrome, Hypermobility Type, and Brugada Syndrome 2 are associated with PECR.

PECR Antibody (2)

    PECR cDNA Clone (30)

    NM_018441.5

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_023523.5

    クローニングベクター cDNA 製品

    In lentiviral vector

    PECR の背景知識

    PECR (Peroxisomal Trans-2-Enoyl-CoA Reductase) is a Protein Coding gene. The PECR gene, located on 2q35, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, K.lactis, M.oryzae, rice, and frog. PECR belongs to the short-chain dehydrogenases/reductases (SDR) family. This protein is involved in the pathway of fatty acid biosynthesis, which is part of Lipid metabolism, it has no 2,4-dienoyl-CoA reductase activity. PECR is widely expressed in the liver), fat, and other tissues. Diseases associated with PECR include Ehlers-Danlos Syndrome, Hypermobility Type, and Brugada Syndrome 2. Among its related pathways are Allograft rejection and Metabolism. 232 organisms have orthologs with the human gene PECR.

    PECR の参考文献

    • Wang W, et al. (2017) Trim37, a novel e3 ligase for pex5-mediated peroxisomal matrix protein import. J Cell Biol 216 (9): 2843-2858.
    • Hua T, et al. (2012) Studies of human 2,4-dienoyl coa reductase shed new light on peroxisomal β-oxidation of unsaturated fatty acids. J Biol Chem 287 (34): 28956-28965.
    • Gloerich J, et al. (2006) Peroxisomal trans-2-enoyl-coa reductase is involved in phytol degradation. FEBS Lett 580 (8): 2092-2096.

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