PDZD11 Proteins, Antibodies, cDNA Clones Research Reagents

PDZD11 (PDZ Domain Containing 11) is a protein coding gene located on human chromosome Xq13.1. PDZD11 is also known as PISP, AIPP1 and PDZK11. The human PDZD11 gene encodes a 16131 Da protein containing 140 amino acids. The PDZD11 protein is ubiquitously expressed in brain, thyroid and other tissues. Among its related pathways are Metabolism of water-soluble vitamins and cofactors and Innate Immune System. PDZD11 is related to protein C-terminus binding. LIN7A is an important paralog of PDZD11 gene. PDZD11 is associated with some diseases, including Purulent Acute Otitis Media and Middle Ear Disease.

PDZD11 Protein (1)

    PDZD11 Antibody (2)

      PDZD11 cDNA Clone (28)

      BC012996

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_028303.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      PDZD11 qPCR Primer (1)

      PDZD11 の背景知識

      PDZ domain-containing protein 11, also known as AIPP1a, PISP, PDZD11 and PDZK11, is a cytosolic protein that contains one PDZ (DHR) domain. PDZD11 bears resemblance to members of the MALS / VELIS family of proteins. It contains but one PDZ domain that apparently interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed, and appears to target calcium and copper ATPases to basolateral cell membranes. PDZD11 is a transiently interacting partner of the PMCA b-splice forms that may play a role in their sorting to or from the plasma membrane. Full-length human PDZD11 shares 97% amino acids (aa) identity with mouse PDZD11.

      PDZD11 の参考文献

      • Goellner,G.M. et al., 2003, Ann N Y Acad Sci. 986 :461-71.
      • Wolf-Yadlin A., et al., 2007, Proc. Natl. Acad. Sci. USA. 104:5860-5.
      • Heibeck T.H., et al.,2009, J. Proteome Res. 8:3852-61.

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