PDAP1 (PDGFA Associated Protein 1) is a Protein Coding gene. The PDAP1 gene, located on 7q22.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDAP1 is widely expressed in fat, colon, and other tissues, and protects mature B cells against chronic ISR activation, and ensures efficient antibody diversification by promoting their survival and optimal function. Among its related pathways are Tyrosine Kinases / Adaptors and Innate Immune System.