PAX3 Antibodies, cDNA Clones Research Reagents

PAX3 (Paired Box 3) is a protein coding gene located on human chromosome 2q36.1. PAX3 is also known as WS1, WS3, CDHS and HUP2. The human PAX3 gene encodes a 52968 Da protein containing 479 amino acids. Among its related pathways are Chromatin organization and Transcriptional misregulation in cancer. PAX3 is related to DNA-binding transcription factor activity and chromatin binding. PAX7 is an important paralog of PAX3 gene. PAX3 is associated with some diseases, including Craniofacial-Deafness-Hand Syndrome and Waardenburg Syndrome, Type 1.

PAX3 Antibody (1)

    PAX3 cDNA Clone (15)


    クローニングベクター cDNA 製品

    In lentiviral vector

    PAX3 qPCR Primer (1)

    PAX3 の背景知識

    The PAX3 gene encodes a member of the PAX family of transcription factors that is characterized by a highly conserved paired box motif. The PAX3 protein is a transcription factor consisting of an N-terminal DNA binding domain (containing a paired box and homeodomain) and a C-terminal transcriptional activation domain. PAX3 is a transcription factor critical to gene regulation in mammalian development. Mutations in PAX3 are associated with Waardenburg syndrome (WS). PAX3 (paired box 3) is known to have an important role in melanocyte development through modulation of microphthalmia-associated transcription factor transcription.

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