PAGE1 (PAGE Family Member 1) is a Protein Coding gene located on Xp11.23. This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. Unlike the other gene family members, this gene does not encode an antigenic peptide. These genes organized in clustered repeats, have a high degree of predicted sequence identity but differ by scattered single nucleotide substitution. Diseases associated with PAGE1 include Ectodermal Dysplasia, Ectrodactyly, And Macular Dystrophy Syndrome, and Noonan Syndrome 1. An important paralog of this gene is GAGE10. 19 organisms have orthologs with human gene PAGE1.