PAGE1 Antibodies, cDNA Clones Research Reagents

PAGE1 (PAGE Family Member 1, also known as AL5; CT16.3; GAGE-9; GAGEB1; PAGE-1), located on Xp11.23, is a Protein Coding gene. This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The gene produces a 16150 Da protein composed of 146 amino acids. The GAGEB1 protein contains 6 potential casein kinase phosphorylation sites, 1 potential protein kinase C phosphorylation site, and 3 potential N-myristoylation sites. Diseases such as Ectodermal Dysplasia, Ectrodactyly, And Macular Dystrophy Syndrome, and Noonan Syndrome 1 are associated with PAGE1.

PAGE1 Antibody (1)

    PAGE1 cDNA Clone (15)

    BC004861

    クローニングベクター cDNA 製品

    In lentiviral vector

    PAGE1 qPCR Primer (1)

    PAGE1 の背景知識

    PAGE1 (PAGE Family Member 1) is a Protein Coding gene located on Xp11.23. This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. Unlike the other gene family members, this gene does not encode an antigenic peptide. These genes organized in clustered repeats, have a high degree of predicted sequence identity but differ by scattered single nucleotide substitution. Diseases associated with PAGE1 include Ectodermal Dysplasia, Ectrodactyly, And Macular Dystrophy Syndrome, and Noonan Syndrome 1. An important paralog of this gene is GAGE10. 19 organisms have orthologs with human gene PAGE1.

    PAGE1 の参考文献

    • De Backer O, et al. (1999) Characterization of the gage genes that are expressed in various human cancers and in normal testis. Cancer Res 59 (13): 3157-3165.
    • Chen ME, et al. (1998) Isolation and characterization of page-1 and gage-7. New genes expressed in the lncap prostate cancer progression model that share homology with melanoma-associated antigens. J Biol Chem 273 (28): 17618-17625.
    • Brinkmann U, et al. (1998) Page-1, an x chromosome-linked gage-like gene that is expressed in normal and neoplastic prostate, testis, and uterus. Proc Natl Acad Sci U S A 95 (18): 10757-10762.

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