OLFML1 Antibodies, cDNA Clones Research Reagents

OLFML1 (Olfactomedin Like 1, also known as UNQ564; MVAL564), located on 11p15.4, is a Protein Coding gene. Olfactomedin-like (OLFML) proteins are members of the olfactomedin domain-containing secreted glycoprotein (OLF) family. The gene produces a 45951 Da protein composed of 402 amino acids. OLFML1 (human olfactomedin-like protein 1), with an olfectamine domain in its C-terminus, is mainly expressed in the small intestine, liver, lung, and heart. Mutation of OLFML1 leads to impaired osteoblast differentiation and abnormal development of bone tissue.

OLFML1 Antibody (1)

    OLFML1 cDNA Clone (13)

    NM_198474.3

    クローニングベクター cDNA 製品

    In lentiviral vector

    OLFML1 qPCR Primer (1)

    OLFML1 の背景知識

    Olfactomedin-like (OLFML) proteins are members of the olfactomedin domain-containing secreted glycoprotein (OLF) family. This family has at least four members. OLFML1 (Olfactomedin Like 1) is a Protein Coding gene. The OLFML1 gene, located on 11p15.4, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, and frog. hOLFML1 (human olfactomedin-like protein 1), with an olfectamine domain in its C-terminus, is mainly expressed in the small intestine, liver, lung, and heart. An important paralog of this gene is OLFML3. OLFML1 is widely expressed in the ovary, gall bladder, and other tissues. Mutation of OLFML1 leads to impaired osteoblast differentiation and abnormal development of bone tissue. 213 organisms have orthologs with the human gene OLFML1.

    OLFML1 の参考文献

    • Wan B, et al. (2008) Holfml1, a novel secreted glycoprotein, enhances the proliferation of human cancer cell lines in vitro. FEBS Lett 582 (21-22): 3185-3192.
    • Rodríguez-Sánchez IP, et al. (2013) Olfactomedin-like 3 (olfml3) gene expression in baboon and human ocular tissues: Cornea, lens, uvea, and retina. J Med Primatol 42 (3): 105-111.
    • Murakami K, et al. (2018) Olfactomedin-like protein olfml1 inhibits hippo signaling and mineralization in osteoblasts. Biochem Biophys Res Commun 505 (2): 419-425.
    • Garza-Rodríguez ML, et al. (2019) Olfactomedin-like 2 a and b (olfml2a and olfml2b) profile expression in the retina of spotted gar (lepisosteus oculatus) and bioinformatics mining. Fish Physiol Biochem 45 (5): 1575-1587.

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