OCIAD2 Antibodies, cDNA Clones Research Reagents

OCIAD2 (OCIA Domain Containing 2), located on 4p11, is a Protein Coding gene. The gene produces a 16954 Da protein composed of 154 amino acids. OCIAD2 has also been reported to show cancer-specific expression in early invasive lung adenocarcinoma. Frequently methylated or downregulated, OCIAD2 has been observed in kinds of tumors, and TGFβ signaling has been proved to induce the expression of OCIAD2. Diseases such as Ovarian Mucinous Neoplasm and Ovarian Cancer are associated with OCIAD2.

OCIAD2 Antibody (1)

    OCIAD2 cDNA Clone (30)

    BC032808

    クローニングベクター cDNA 製品

    In lentiviral vector

    XM_002709431.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    OCIAD2 qPCR Primer (1)

    OCIAD2 の背景知識

    Ovarian cancer immunoreactive antigen domain containing 2 (OCIAD2) is a Protein Coding gene. The OCIAD2 gene, located on 4p11, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, and frog. Frequently methylated or downregulated, OCIAD2 has been observed in kinds of tumors, and TGFβ signaling has been proved to induce the expression of OCIAD2. OCIAD2 has been found frequently methylated in various cancers, including hepatocellular carcinoma (HCC). OCIAD2 has also been reported to show cancer-specific expression in early invasive lung adenocarcinoma. Diseases associated with OCIAD2 include Ovarian Mucinous Neoplasm and Ovarian Cancer. An important paralog of this gene is OCIAD1. 210 organisms have orthologs with the human gene OCIAD2.

    OCIAD2 の参考文献

    • Zhang R, et al. (2014) Pathway bridge based multiobjective optimization approach for lurking pathway prediction. Biomed Res Int 2014 351095.
    • Wu D, et al. (2017) Ociad2 suppressed tumor growth and invasion via akt pathway in hepatocelluar carcinoma. Carcinogenesis 38 (9): 910-919.
    • Nagata C, et al. (2012) Increased expression of ocia domain containing 2 during stepwise progression of ovarian mucinous tumor. Pathol Int 62 (7): 471-476.

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