Coronavirus NSP8 Proteins, cDNA Clones Research Reagents

All Coronavirus NSP8 reagents are produced in house and quality controlled, including 1 Coronavirus NSP8 Gene, 1 Coronavirus NSP8 Protein. All Coronavirus NSP8 reagents are ready to use.

Coronavirus NSP8 Protein (1)

    Coronavirus NSP8 cDNA Clone (1)

    SARS-CoV-2

    In expression vector

    Coronavirus NSP8 の背景知識

    NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarkably stimulates RdRp activity. The nsp12-nsp7-nsp8 subcomplex is defined as the minimal core component for mediating coronavirus RNA synthesis.

    Coronavirus NSP8 の参考文献

    • Qi Peng,et al.Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2.Cell Reports.2020
    • Yan Gao,et al.Structure of the RNA-dependent RNA polymerase from COVID-19 virus.Science.2020
    • Purnima Kumar,et al.The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein.Virology.2007

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