NRG3 Proteins, Antibodies, cDNA Clones Research Reagents

NRG3 (Neuregulin 3, also known as HRG3; pro-NRG3), located on 10q23.1, is conserved in Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. The gene produces a 77901 Da protein composed of 720 amino acids. This gene is a member of the neuregulin gene family. Neuregulins, including NRG3, form a family of neurally expressed proteins that perform a wide range of functions in the developing nervous system. Diseases such as Schizophrenia and Schizoaffective Disorder are associated with NRG3. The related pathways of NRG3 include RET signaling and Signaling by GPCR.

NRG3 Protein (2)

    NRG3 Antibody (3)

      NRG3 cDNA Clone (13)

      NM_001010848.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      NRG3 Lysate (2)

        NRG3 の背景知識

        NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signaling through ERBB4. NRG3, a brain-enriched neurotrophin, undergoes alternative splicing and is implicated in several neurological disorders with developmental origins. It also promotes mammary differentiation during embryogenesis. NRG3 promotes early mammary morphogenesis and acts during specification of the mammary placode, an aggregate of epithelial cells that form during mid-embryogenesis. Diseases associated with NRG3 include Schizophrenia and Schizoaffective Disorder.

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