NOX4 Antibodies, cDNA Clones Research Reagents

NOX4 (NADPH Oxidase 4, also known as KOX; KOX-1; RENOX), located on 11q14.3, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, mosquito, and frog. The gene produces a 66932 Da protein composed of 578 amino acids. This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit of the NADPH oxidase complex. Diseases such as Ureteral Obstruction and Pulmonary Hypertension are associated with NOX4. The related pathways of NOX4 include Detoxification of Reactive Oxygen Species and Human Embryonic Stem Cell Pluripotency.

NOX4 Antibody (2)

    NOX4 cDNA Clone (27)

    BC040105

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_015760.5

    クローニングベクター cDNA 製品

    In lentiviral vector

    NOX4 qPCR Primer (1)

    NOX4 の背景知識

    NOX4 (NADPH Oxidase 4) is a Protein Coding gene. This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit of the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). NOX4 has emerged as a significant source of reactive oxygen species, playing an important role in tumor cell proliferation, apoptosis, and other physiological processes. Its expression is increased in sepsis. NOX4 also plays a major role in renal oxidative stress of diabetic kidney disease (DKD). Diseases associated with NOX4 include Ureteral Obstruction and Pulmonary Hypertension.

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