NGF Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All NGF reagents are produced in house and quality controlled, including 18 NGF Antibody, 2 NGF ELISA, 51 NGF Gene, 3 NGF Lysate, 4 NGF Protein, 3 NGF qPCR. All NGF reagents are ready to use.

NGF Protein (4)

    NGF Antibody (18)

      NGF ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(2)

      NGF cDNA Clone (51)

      NM_002506.2
      NM_001112698.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_001277055.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_001194950.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      NGF Lysate (3)

        NGF の背景知識

        Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In addition, previous studies indicated that NGF may also have an important role in the regulation of the immune system.

        NGF の参考文献

        • Castellanos MR, et al. (2003) Evaluation of the neurorestorative effects of the murine beta-nerve growth factor infusions in old rat with cognitive deficit. Biochem Biophys Res Commun. 312(4): 867-72.
        • Wang TH, et al. (2008) Effects of pcDNA3-beta-NGF gene-modified BMSC on the rat model of Parkinson's disease. J Mol Neurosci. 35(2): 161-9.
        • Perrard MH, et al. (2009) Redundancy of the effect of TGFbeta1 and beta-NGF on the second meiotic division of rat spermatocytes. Microsc Res Tech. 72(8): 596-602.

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