Myoglobin Antibodies, cDNA Clones Research Reagents

MB (Myoglobin, also known as PVALB), located on 22q12.3, is a Protein Coding gene. The encoded protein forms a monomeric globular haemoprotein that is primarily responsible for the storage and facilitated the transfer of oxygen from the cell membrane to the mitochondria. It belongs to the globin family. This protein also plays a role in regulating physiological levels of nitric oxide. Myoglobin is an important intracellular oxygen-binding hemoprotein found in the cytoplasm of skeletal and cardiac muscle tissue playing a well-known role in O(2) storage and delivery.

Myoglobin Antibody (1)

    Myoglobin cDNA Clone (28)

    NM_203378.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_001164047.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_021588.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    Myoglobin qPCR Primer (1)

    Myoglobin の背景知識

    MB (Myoglobin) is a Protein Coding gene. The MB gene, located on 22q12.3, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and zebrafish. Myoglobin is an important intracellular oxygen-binding hemoprotein found in the cytoplasm of skeletal and cardiac muscle tissue playing a well-known role in O(2) storage and delivery. This gene encodes a member of the globin superfamily and is predominantly expressed in skeletal and cardiac muscles. The encoded protein forms a monomeric globular haemoprotein that is primarily responsible for the storage and facilitated the transfer of oxygen from the cell membrane to the mitochondria. This protein also plays a role in regulating physiological levels of nitric oxide. Diseases associated with MB include Compartment Syndrome and Medullomyoblastoma.

    Myoglobin の参考文献

    • Yamada T, et al. (2016) Myoglobin and the regulation of mitochondrial respiratory chain complex iv. J Physiol 594 (2): 483-495.
    • Olivé M, et al. (2019) Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions. Nat Commun 10 (1): 1396.
    • Flögel U, et al. (2010) Keeping the heart in balance: The functional interactions of myoglobin with nitrogen oxides. J Exp Biol 213 (Pt 16): 2726-2733.

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