Myeloperoxidase/MPO Proteins, Antibodies, cDNA Clones Research Reagents

All Myeloperoxidase/MPO reagents are produced in house and quality controlled, including 2 Myeloperoxidase/MPO Antibody, 3 Myeloperoxidase/MPO Gene, 1 Myeloperoxidase/MPO IP Kit, 2 Myeloperoxidase/MPO Lysate, 2 Myeloperoxidase/MPO Protein, 1 Myeloperoxidase/MPO qPCR. All Myeloperoxidase/MPO reagents are ready to use.

Myeloperoxidase/MPO Protein (2)

    Myeloperoxidase/MPO Antibody (2)

      Myeloperoxidase/MPO cDNA Clone (3)

      BC130476

      In expression vector

      In lentiviral vector

      NM_000250.1

      In expression vector

      Myeloperoxidase/MPO qPCR Primer (1)

      Myeloperoxidase/MPO Lysate (2)

        Myeloperoxidase/MPO の背景知識

        MPO (myeloperoxidase) is a peroxidase enzyme secreted by activated leukocytes that plays a pathogenic role in cardiovascular disease, mainly by initiating endothelial dysfunction.Myeloperoxidase (MPO) is an important enzyme, which is one of the components of the antibacterial system in neutrophils and monocytes. MPO participates in the inflammatory response in multiple locations in the body, including the mammary glands.Myeloperoxidase (MPO), a specific polymorphonuclear leukocyte enzyme, has been used previously to quantify the number of neutrophils in tissue. MPO activity was found to be linearly related to the number of neutrophil cells.The MPO system plays an important role in the control of infections and the deletion of malignant cells. Nevertheless, alternations in the MPO system can lead to DNA damage and carcinogenesis. Polymorphisms in the MPO Gene have been associated with an increased expression of MPO and a higher risk for development of cancer.Myeloperoxidase (MPO) is one of the major target antigens of antineutrophil cytoplasmic autoantibodies (ANCA) found in patients with small-vessel vasculitis and pauci-immune necrotizing glomerulonephritis.Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) is an autoantibody that is frequently found in patients with vasculitides.

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