MSX1 Antibodies, cDNA Clones Research Reagents

MSX1 (Msh Homeobox 1, also known as HOX7; HYD1; ECTD3; STHAG1), located on 4p16.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. The gene produces a 31496 Da protein composed of 303 amino acids. This gene encodes a member of the muscle segment homeobox gene family. Hox7 is expressed in the heart valves, mandibular and hyoid arches, and limb buds during normal murine development. Diseases such as Witkop Syndrome and Orofacial Cleft 5 are associated with MSX1. The related pathways of MSX1 include Neuroscience and Neural Crest Differentiation.

MSX1 Antibody (1)

    MSX1 cDNA Clone (15)

    NM_002448.3

    クローニングベクター cDNA 製品

    In lentiviral vector

    MSX1 qPCR Primer (1)

    MSX1 の背景知識

    MSX1 (Msh Homeobox 1) is a Protein Coding gene. This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. MSX1 is one of the homeoproteins with the homeodomain (HD) sequence, which regulates proliferation and differentiation of mesenchymal cells. MSX1 encodes a transcription factor implicated in the embryonic development of limbs and craniofacial tissues including bone and teeth. The Msx1 transcription factor is involved in multiple epithelial-mesenchymal interactions during vertebrate embryogenesis. It has pleiotropic effects in several tissues. MSX1 has been proposed as a gene in which mutations may contribute to non-syndromic forms of cleft lip and/or cleft palate.

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