MST1 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

STK4 (Serine/Threonine Kinase 4) is a protein coding gene located on human chromosome 20q13.12. STK4 is also known as KRS2, MST1 and YSK3. The human STK4 gene encodes a 55630 Da protein containing 487 amino acids. The STK4 protein is broadly expressed in lymph node, appendix and other tissues. Among its related pathways are Sweet Taste Signaling and Signaling by GPCR. STK4 is related to protein homodimerization activity and transferase activity, transferring phosphorus-containing groups. STK3 is an important paralog of STK4 gene. STK4 is associated with some diseases, including T-Cell Immunodeficiency, Recurrent Infections, And Autoimmunity With Or Without Cardiac Malformations and Lung Cancer.

MST1 Protein (1)

    MST1 Antibody (8)

      MST1 ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(1)

      MST1 cDNA Clone (15)

      NM_006282.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      MST1 qPCR Primer (1)

      MST1 Lysate (1)

        MST1 の背景知識

        Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates TLR3/4/9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a diagnostic biomarker and therapeutic target for inflammation-induced HCC.

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