RPS6KA5 (Ribosomal Protein S6 Kinase A5, also known as MSK1) is a Protein Coding gene. The RPS6KA5 gene, located on 14q32.11, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, chicken, zebrafish, fruit fly, C.elegans, and frog. RPS6KA5 is a serine/threonine kinase that has been reported to be associated with tumor progression in several types of human cancer. RPS6KA5 is widely expressed in the brain, endometrium, and other tissues. Diseases associated with RPS6KA5 include Septic Myocarditis and Coffin-Lowry Syndrome. Among its related pathways are Adenylate cyclase inhibitory pathway and Nuclear Events (kinase and transcription factor activation). 216 organisms have orthologs with the human gene RPS6KA5.