MRPL44 Proteins, Antibodies, cDNA Clones Research Reagents

MRPL44 (Mitochondrial Ribosomal Protein L44, also known as L44MT; COXPD16; MRP-L44), located on 2q36.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog. The gene produces a 37535 Da protein composed of 332 amino acids. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Diseases such as Combined Oxidative Phosphorylation Deficiency 16 and Combined Oxidative Phosphorylation Deficiency 1 are associated with MRPL44. The related pathways of MRPL44 include Organelle biogenesis and maintenance and Mitochondrial translation.

MRPL44 Protein (1)

    MRPL44 Antibody (1)

      MRPL44 cDNA Clone (15)

      BC012058

      クローニングベクター cDNA 製品

      In lentiviral vector

      MRPL44 qPCR Primer (1)

      MRPL44 Lysate (1)

        MRPL44 の背景知識

        MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondrial ribosome. It belongs to the mitochondrion-specific ribosomal protein mL44 subfamily. In the patient fibroblasts, decreased MRPL44 affected assembly of the large ribosomal subunit and stability of 16S rRNA leading to complex IV deficiency. It may have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome. MRPL44 is widely expressed in the bone marrow, lymph node, and other tissues. Diseases associated with MRPL44 include Combined Oxidative Phosphorylation Deficiency 16 and Combined Oxidative Phosphorylation Deficiency 1.

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