MRPL34 Antibodies, cDNA Clones Research Reagents

MRPL34 (Mitochondrial Ribosomal Protein L34, also known as L34mt), located on 19p13.1, is a Protein Coding gene. This gene encodes a 39S subunit protein and is widely expressed in the kidney, duodenum, and other tissues. MRPL34 is 1 of more than 70 protein components of mitochondrial ribosomes that are encoded by the nuclear genome. MRPL34 belongs to the bacterial ribosomal protein bL34 family. Diseases such as Bardet-Biedl Syndrome 5 is associated with MRPL34. The related pathways include the Organelle biogenesis and maintenance and Viral mRNA Translation.

MRPL34 Antibody (1)

    MRPL34 cDNA Clone (17)

    NM_023937.3

    クローニングベクター cDNA 製品

    In lentiviral vector

    XM_004761043.1

    クローニングベクター cDNA 製品

    In lentiviral vector

    MRPL34 の背景知識

    MRPL34 (Mitochondrial Ribosomal Protein L34) is a Protein Coding gene. The MRPL34 gene, located on 19p13.1, is conserved in chimpanzee, Rhesus monkey, cow, mouse, and rat. MRPL34 belongs to the bacterial ribosomal protein bL34 family. This gene encodes a 39S subunit protein. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL34 is widely expressed in the kidney, duodenum, and other tissues. Diseases associated with MRPL34 include Bardet-Biedl Syndrome 5. Among its related pathways are Organelle biogenesis and maintenance and Viral mRNA Translation. 212 organisms have orthologs with the human gene MRPL34.

    MRPL34 の参考文献

    • Suzuki T, et al. (2001) Structural compensation for the deficit of rrna with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. J Biol Chem 276 (24): 21724-21736.
    • Kenmochi N, et al. (2001) The human mitochondrial ribosomal protein genes: Mapping of 54 genes to the chromosomes and implications for human disorders. Genomics 77 (1-2): 65-70.
    • Graack HR, et al. (1999) Identification of mammalian mitochondrial ribosomal proteins (mrps) by n-terminal sequencing of purified bovine mrps and comparison to data bank sequences: The large subribosomal particle. Biochemistry 38 (50): 16569-16577.

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