MRGPRF Antibodies, cDNA Clones Research Reagents

MRGPRF (MAS Related GPR Family Member F, also known as RTA; MRGF; GPR140; GPR168), located on 11q13.3, is a Protein Coding gene. The encoded protein is an orphan receptor. MRGPRF may bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain. MRGPRF belongs to the G-protein coupled receptor 1 family, Mas subfamily. MRGPRF is one of the G-protein coupled receptor signaling pathway-related genes, which is found to be down-regulated in early-onset preeclampsia.

MRGPRF Antibody (1)

    MRGPRF cDNA Clone (15)

    NM_145015

    In expression vector

    In lentiviral vector

    NM_153722.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    MRGPRF qPCR Primer (1)

    MRGPRF の背景知識

    MRGPRF (MAS Related GPR Family Member F) is a Protein Coding gene. The MRGPRF gene, located on 11q13.3, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat. MRGPRF belongs to the G-protein coupled receptor 1 family. The encoded protein is an orphan receptor. It may bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity). MRGPRF is one of the G-protein coupled receptor signaling pathway-related genes, which is found to be down-regulated in early-onset preeclampsia. MRGPRF is widely expressed in the endometrium, prostate, and other tissues. Diseases associated with MRGPRF include Isolated Growth Hormone Deficiency, Type Ib.

    MRGPRF の参考文献

    • Ross PC, et al. (1990) Rta, a candidate g protein-coupled receptor: Cloning, sequencing, and tissue distribution. Proc Natl Acad Sci U S A 87 (8): 3052-3056.
    • Otsuki T, et al. (2005) Signal sequence and keyword trap in silico for selection of full-length human cdnas encoding secretion or membrane proteins from oligo-capped cdna libraries. DNA Res 12 (2): 117-126.
    • Liang M, et al. (2016) Gene expression profiling reveals different molecular patterns in g-protein coupled receptor signaling pathways between early- and late-onset preeclampsia. Placenta 40 52-59.

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