Motilin Proteins, Antibodies, cDNA Clones Research Reagents

MLN (Motilin), located on 6p21.31, is conserved in chimpanzee, Rhesus monkey, dog, and cow. The gene produces a 12920 Da protein composed of 115 amino acids. This gene encodes a small peptide hormone that is secreted by cells of the small intestine to regulate gastrointestinal contractions and motility. The predicted amino acid sequence indicated that the motilin precursor includes a 25-residue N-terminal signal peptide followed by the 22-amino acid motilin sequence and a long, 68-residue C-terminal peptide. Diseases such as Gastroparesis and Duodenogastric Reflux are associated with MLN.

Motilin Protein (1)

    Motilin Antibody (1)

      Motilin cDNA Clone (13)

      BC112314

      クローニングベクター cDNA 製品

      In lentiviral vector

      Motilin qPCR Primer (1)

      Motilin Lysate (1)

        Motilin の背景知識

        MLN (Motilin) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. This gene encodes a small peptide hormone that is secreted by cells of the small intestine to regulate gastrointestinal contractions and motility. The encoded protein belongs to the motilin family. Proteolytic processing of the secreted protein produces the mature peptide and a byproduct referred to as motilin-associated peptide (MAP). MLN plays an important role in the regulation of Interdigestive Gastrointestinal Motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle. Diseases associated with MLN include Gastroparesis and Duodenogastric Reflux. Among its related pathways are RET signaling and Signaling by GPCR.

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