MCM8 Antibodies, cDNA Clones Research Reagents

MCM8 (Minichromosome Maintenance 8 Homologous Recombination Repair Factor, also known as POF10; C20orf154; dJ967N21.5), located on 20p12.3, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, A.thaliana, rice, and frog. The gene produces a 93697 Da protein composed of 840 amino acids. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. Diseases such as Premature Ovarian Failure 10 and Amenorrhea are associated with MCM8.

MCM8 Antibody (1)

    MCM8 cDNA Clone (15)

    BC080656

    クローニングベクター cDNA 製品

    In lentiviral vector

    MCM8 qPCR Primer (1)

    MCM8 の背景知識

    MCM8 (Minichromosome Maintenance 8 Homologous Recombination Repair Factor, also known as POF10 and C20orf154) is a Protein Coding gene. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. MCM8 is a new family member, not present in yeast, which may function alone or with other family members in aspects of DNA metabolism, including replication initiation and elongation. MCM8, a component of the pre-replication complex, is crucial for gonadal development and maintenance in humans-both males and females. MCM8 is broadly expressed in the testis, lymph node, and other tissues. Diseases associated with MCM8 include Premature Ovarian Failure 10 and Amenorrhea.

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