MAPK11 Antibodies, cDNA Clones Research Reagents

MAPK11 (Mitogen-Activated Protein Kinase 11, also known as P38B; SAPK2; p38-2; PRKM11; SAPK2B; p38Beta; P38BETA2), located on 22q13.33, is conserved in Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana, and frog. The gene produces a 41357 Da protein composed of 364 amino acids. This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. Diseases such as Syphilitic Meningitis are associated with MAPK11. The related pathways of MAPK11 include ATM Pathway and Organelle biogenesis and maintenance.

MAPK11 Antibody (1)

    MAPK11 cDNA Clone (16)

    NM_002751.6

    In expression vector

    NM_011161.5

    クローニングベクター cDNA 製品

    In lentiviral vector

    MAPK11 の背景知識

    The p38 kinases are one of the four subgroups of the mitogen-activated protein kinase (MAPK) superfamily which are involved in innate immunity. The p38 subfamily includes four members namely p38alpha (MAPK14), p38beta (MAPK11), p38gamma (MAPK12), and p38delta (MAPK13), regulates the activation of several transcription factors. MAPK11 (Mitogen-Activated Protein Kinase 11) is a Protein Coding gene. This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. MAPK11 is widely expressed in fat, the brain, and other tissues. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen-activated protein kinase kinases (MKKs).

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