LSM7 Antibodies, cDNA Clones Research Reagents

LSM7 (LSM7 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated, also known as YNL147W), located on 19p13.3, is a Protein Coding gene. The encoded protein plays role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as a component of the pre catalytic spliceosome (spliceosome B complex). It belongs to the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop.

LSM7 Antibody (1)

    LSM7 cDNA Clone (15)

    BC018621

    クローニングベクター cDNA 製品

    In lentiviral vector

    LSM7 qPCR Primer (1)

    LSM7 の背景知識

    LSM7 (LSM7 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. The LSM7 gene, located on 19p13.3, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, and zebrafish, etc. LSM7 belongs to the snRNP Sm proteins family. LSM7 plays role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as a component of the pre catalytic spliceosome (spliceosome B complex). LSM7 is widely expressed in the colon, bone marrow, and other tissues. Diseases associated with LSM7 include Spermatogenic Failure 5. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway.

    LSM7 の参考文献

    • Scheller N, et al. (2009) Translation and replication of hepatitis c virus genomic rna depends on ancient cellular proteins that control mrna fates. Proc Natl Acad Sci U S A 106 (32): 13517-13522.
    • Conte N, et al. (2003) Tacc1-chtog-aurora a protein complex in breast cancer. Oncogene 22 (50): 8102-8116.
    • Conte N, et al. (2002) Carcinogenesis and translational controls: Tacc1 is down-regulated in human cancers and associates with mrna regulators. Oncogene 21 (36): 5619-5630.

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