KLK15 Proteins, cDNA Clones Research Reagents

KLK15 (Kallikrein Related Peptidase 15, also known as ACO; HSRNASPH), located on 19q13.33, is a Protein Coding gene. The gene produces a 28087 Da protein composed of 256 amino acids. KLK15 belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. KLK15 over-expression is reported to be a significant predictor of reduced progression-free survival and overall survival in ovarian cancer. Diseases such as Prostate Cancer and Peripheral Vascular Disease are associated with KLK15. The related pathways of KLK15 include Collagen chain trimerization and MSP-RON Signaling.

KLK15 Protein (2)

    KLK15 cDNA Clone (2)

    BC126137

    In expression vector

    In lentiviral vector

    KLK15 qPCR Primer (1)

    KLK15 Lysate (2)

      KLK15 の背景知識

      KLK15 (Kallikrein Related Peptidase 15) is a Protein Coding gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Human KLK15 may have some utility as a prostate, ovarian, and breast cancer biomarker, based on previous studies, which examined mRNA levels of KLK15. Aberrant KLK15 expression is found in breast, ovarian, and prostate cancers. KLK15 over-expression is reported to be a significant predictor of reduced progression-free survival and overall survival in ovarian cancer. Kallikrein 15 (KLK15)/Prostinogen is a plausible candidate for prostate cancer susceptibility. Elevated KLK15 expression has been reported in prostate cancer and it has been described as an unfavorable prognostic marker for the disease.

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