KIAA1279 Proteins, Antibodies, cDNA Clones Research Reagents

KIFBP (Kinesin Family Binding Protein, also known as KBP; TTC20; KIF1BP; KIAA1279), located on 10q22.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog. The gene produces a 71814 Da protein composed of 621 amino acids. The KIFBP gene encodes a ubiquitously expressed protein that interacts with microtubules. The encoded protein shares 89% sequence homology with the mouse homolog. The predicted protein contains 2 tetratricopeptide repeats.

KIAA1279 Protein (2)

    KIAA1279 Antibody (2)

      KIAA1279 cDNA Clone (1)


      In expression vector

      KIAA1279 Lysate (2)

        KIAA1279 の背景知識

        KIFBP (Kinesin Family Binding Protein, also known as KIAA1279 and KIF1BP) is a Protein Coding gene. This gene encodes a kinesin family member 1 binding protein that is characterized by two tetratricopeptide repeats. The encoded protein localizes to the mitochondria and may be involved in regulating the transport of the mitochondria. Homozygous nonsense mutations in KIAA1279 at 1q22.1, encoding a protein with two tetratricopeptide repeats, underlie this syndromic form of Hirschsprung disease and generalized polymicrogyria, establishing the importance of KIAA1279 in both enteric and central nervous system development. KIAA1279 is widely expressed in the brain, testis, and other tissues. Diseases associated with KIFBP include Goldberg-Shprintzen Syndrome and Shprintzen-Goldberg Craniosynostosis Syndrome.

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