INHBE Proteins, cDNA Clones Research Reagents

INHBE (Inhibin Subunit Beta E), located on 12q13.3, is a Protein Coding gene. The gene produces a 38561 Da protein composed of 350 amino acids. INHBE is a member of the activin beta family that plays a role in pancreatic exocrine cell growth and proliferation. The protein contains an N-terminal hydrophobic signal peptide and a potential N-glycosylation site. INHBE shares 97% and 96% similarity with the mouse and rat activin beta-E orthologs, respectively. Diseases such as Brachydactyly, Type A2, and Liver Benign Neoplasm are associated with INHBE.

INHBE Protein (1)

    INHBE cDNA Clone (26)


    クローニングベクター cDNA 製品

    In lentiviral vector


    クローニングベクター cDNA 製品

    In lentiviral vector

    INHBE Lysate (1)

      INHBE の背景知識

      INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. INHBE was identified as a novel putative hepatokine with hepatic gene expression that positively correlated with insulin resistance and body mass index in humans. The quantitative real time-PCR analysis also showed an increase in INHBE gene expression in independent liver samples from insulin-resistant human subjects. INHBE functions as a possible hepatokine to alter the whole-body metabolic status under obese insulin-resistant conditions. Diseases associated with INHBE include Brachydactyly, Type A2, and Liver Benign Neoplasm.

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