INHBE Proteins, cDNA Clones Research Reagents

INHBE (Inhibin Subunit Beta E), located on 12q13.3, is a Protein Coding gene. The gene produces a 38561 Da protein composed of 350 amino acids. INHBE is a member of the activin beta family that plays a role in pancreatic exocrine cell growth and proliferation. The protein contains an N-terminal hydrophobic signal peptide and a potential N-glycosylation site. INHBE shares 97% and 96% similarity with the mouse and rat activin beta-E orthologs, respectively. Diseases such as Brachydactyly, Type A2, and Liver Benign Neoplasm are associated with INHBE.

INHBE Protein (1)

    INHBE cDNA Clone (26)

    NM_031479.3

    クローニングベクター cDNA 製品

    In lentiviral vector

    NM_008382.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    INHBE Lysate (1)

      INHBE の背景知識

      INHBE (Inhibin Subunit Beta E) is a Protein Coding gene. This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate an inhibin beta subunit. INHBE was identified as a novel putative hepatokine with hepatic gene expression that positively correlated with insulin resistance and body mass index in humans. The quantitative real time-PCR analysis also showed an increase in INHBE gene expression in independent liver samples from insulin-resistant human subjects. INHBE functions as a possible hepatokine to alter the whole-body metabolic status under obese insulin-resistant conditions. Diseases associated with INHBE include Brachydactyly, Type A2, and Liver Benign Neoplasm.

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