IL1RL2 Proteins, cDNA Clones Research Reagents

IL1RL2 (Interleukin 1 Receptor-Like 2, also known as IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2), located on 2q12.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and zebrafish. The gene produces a 65405 Da protein composed of 575 amino acids. The protein encoded by this gene is a member of the interleukin 1 receptor family. Diseases such as Familial Cold Autoinflammatory Syndrome 2 and Geographic Tongue are associated with IL1RL2. The related pathways of IL1RL2 include PEDF Induced Signaling and the Innate Immune System.

IL1RL2 Protein (2)

    IL1RL2 cDNA Clone (13)

    NM_003854.2

    クローニングベクター cDNA 製品

    In lentiviral vector

    IL1RL2 qPCR Primer (1)

    IL1RL2 Lysate (2)

      IL1RL2 の背景知識

      IL1RL2 (Interleukin 1 Receptor-Like 2, also known as IL-36R) is a Protein Coding gene. The protein encoded by this gene is a member of the interleukin 1 receptor family. This gene and four other interleukin 1 receptor family genes form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. The IL36 receptor is an important mediator molecule in the inflammatory response. Animal data suggest that IL1RL2 is involved in mucosal healing. Therapeutic intervention of IL-36R signaling offers an innovative treatment paradigm for targeting epithelial cell-mediated inflammatory diseases such as the life-threatening psoriasis variant called generalized pustular psoriasis (GPP). Diseases associated with IL1RL2 include Familial Cold Autoinflammatory Syndrome 2 and Geographic Tongue.

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