IGSF3 Proteins, Antibodies, cDNA Clones Research Reagents

All IGSF3 reagents are produced in house and quality controlled, including 8 IGSF3 Antibody, 13 IGSF3 Gene, 1 IGSF3 Lysate, 1 IGSF3 Protein, 1 IGSF3 qPCR. All IGSF3 reagents are ready to use.

IGSF3 Protein (1)

    IGSF3 Antibody (8)

      IGSF3 cDNA Clone (13)


      クローニングベクター cDNA 製品

      In lentiviral vector

      IGSF3 qPCR Primer (1)

      IGSF3 Lysate (1)

        IGSF3 の背景知識

        Immunoglobulin superfamily member 3 (IGSF3), also known as Glu-Trp-Ile EWI motif-containing protein 3, IgSF3 and EWI-3 and IGSF3, is a single-pass type I membrane protein which belongs to the EWI subfamily of the Ig Superfamily of molecules. IGSF3 has an overall structural similarity and strong sequence similarity to V7, a human leukocyte surface protein. IGSF3 contains eight Ig-like C2-type (immunoglobulin-like) domains. IGSF3 is expressed in a wide range of tissues with high expression in Placenta, kidney and lung. EWI-2 is part of a novel Ig subfamily that includes EWI-F (F2alpha receptor regulatory protein (FPRP), CD9P-1 ), EWI-3 (IGSF3), and EWI-11 (CD11). All four members of this Ig subfamily contain a Glu-Trp-Ile (EWI) motif not seen in other Ig proteins. Human IGSF3 shares 92 % aa identity with mouse IGSF3.

        IGSF3 の参考文献

        • Saupe S, et al. (1998) Molecular cloning of a human cDNA IGSF3 encoding an immunoglobulin-like membrane protein: expression and mapping to chromosome band 1p13. Genomics. 52(3): 305-11.
        • Lazaar AL, et al. (2001) VCAM-1 activates phosphatidylinositol 3-kinase and induces p120Cbl phosphorylation in human airway smooth muscle cells. J Immunol. 166(1): 155-61.
        • Wetzel A, et al. (2004) Human Thy-1 (CD90) on activated endothelial cells is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18). J Immunol. 172(6): 3850-9.

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