IGSF3 Proteins, Antibodies, cDNA Clones Research Reagents

All IGSF3 reagents are produced in house and quality controlled, including 8 IGSF3 Antibody, 13 IGSF3 Gene, 1 IGSF3 Lysate, 1 IGSF3 Protein, 1 IGSF3 qPCR. All IGSF3 reagents are ready to use.

IGSF3 Protein (1)

    IGSF3 Antibody (8)

      IGSF3 cDNA Clone (13)

      NM_001007237.1

      クローニングベクター cDNA 製品

      In lentiviral vector

      IGSF3 qPCR Primer (1)

      IGSF3 Lysate (1)

        IGSF3 の背景知識

        Immunoglobulin superfamily member 3 (IGSF3), also known as Glu-Trp-Ile EWI motif-containing protein 3, IgSF3 and EWI-3 and IGSF3, is a single-pass type I membrane protein which belongs to the EWI subfamily of the Ig Superfamily of molecules. IGSF3 has an overall structural similarity and strong sequence similarity to V7, a human leukocyte surface protein. IGSF3 contains eight Ig-like C2-type (immunoglobulin-like) domains. IGSF3 is expressed in a wide range of tissues with high expression in Placenta, kidney and lung. EWI-2 is part of a novel Ig subfamily that includes EWI-F (F2alpha receptor regulatory protein (FPRP), CD9P-1 ), EWI-3 (IGSF3), and EWI-11 (CD11). All four members of this Ig subfamily contain a Glu-Trp-Ile (EWI) motif not seen in other Ig proteins. Human IGSF3 shares 92 % aa identity with mouse IGSF3.

        IGSF3 の参考文献

        • Saupe S, et al. (1998) Molecular cloning of a human cDNA IGSF3 encoding an immunoglobulin-like membrane protein: expression and mapping to chromosome band 1p13. Genomics. 52(3): 305-11.
        • Lazaar AL, et al. (2001) VCAM-1 activates phosphatidylinositol 3-kinase and induces p120Cbl phosphorylation in human airway smooth muscle cells. J Immunol. 166(1): 155-61.
        • Wetzel A, et al. (2004) Human Thy-1 (CD90) on activated endothelial cells is a counterreceptor for the leukocyte integrin Mac-1 (CD11b/CD18). J Immunol. 172(6): 3850-9.

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