IFNA7 Proteins, cDNA Clones Research Reagents

IFNA7 (Interferon Alpha 7, also known as IFNA-J; IFN-alphaJ), located on 9p21.3, is a Protein Coding gene. The gene produces a 22107 Da protein composed of 189 amino acids. Human IFN is divided on the sequence of amino-acids into three groups: Alpha, Beta, and Gamma interferons. Produced by macrophages, IFN-alpha has antiviral activities. IFNA7 is a member of the interferon family. Diseases such as Acute Hemorrhagic Conjunctivitis are associated with IFNA7. The related pathways of IFNA7 include all-trans-retinoic Acid Mediated Apoptosis and Tuberculosis.

IFNA7 Protein (2)

    IFNA7 cDNA Clone (13)


    クローニングベクター cDNA 製品

    In lentiviral vector

    IFNA7 qPCR Primer (1)

    IFNA7 Lysate (1)

      IFNA7 の背景知識

      Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs have other functions: they activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they increase the ability of uninfected host cells to resist new infection by the virus. Certain host symptoms, such as aching muscles and fever, are related to the production of IFNs during infection. Human IFN is divided on the sequence of amino-acids into three groups: Alpha, Beta, and Gamma interferons.

      IFNA7 の参考文献

      • De Veer MJ, et al. (2001) Functional classification of interferon-stimulated genes identified using microarrays. J Leukoc Biol. 69 (6): 912-20.
      • Liu YJ. (2005) IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. Annu Rev Immunol. 23: 275-306.
      • Fensterl V, et al. (2009) Interferons and viral infections. Biofactors. 35 (1): 14-20.

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